20-year-old midfielder Keaton Parks has earned his first call-up to Benfica's senior squad. The American has been in excellent form for Benfica B, and clearly impressed Rui Vitória whilst training with the first team during the international break.
Rúben Dias has been suffering from acute appendicitis and was forced to undergo surgery this morning. Mile Svilar has a virus and Júlio César is still battling with his chronic back condition. Andrija Živković has been left out completely, as rumours continue to swirl about a contractual dispute relating to bonus payments.
Eliseu, Filipe Augusto and Ljubomir Fejsa are all rested, while Lisandro López, Rafa Silva and Gabriel Barbosa return.
Saturday's match at the Estádio da Luz begins at 18:15 local time.
Goalkeepers: Bruno Varela and Paulo Lopes
Defenders: Lisandro, Grimaldo, Luisão, Douglas, André Almeida and Jardel
Midfielders: Samaris, Salvio, Krovinović, Pizzi, Cervi, Keaton Parks, Rafa Silva and Diogo Gonçalves
Forwards: Raúl, Jonas, Gabriel Barbosa and Seferović