Mile Svilar has recovered from a bout of flu and replaces Fábio Duarte. Rúben Dias is still recovering after having his appendix removed, while Lisandro López has been dropped.
Filipe Augusto is sidelined with a right foot injury. Filip Krovinović and Keaton Parks return in place of Rafa Silva and João Carvalho.
Sunday's game at the Estádio da Luz commences at 20:15 local time.
Goalkeepers: Svilar and Bruno Varela
Defenders: Grimaldo, Luisão, Douglas, Eliseu, Jardel and André Almeida
Midfielders: Fejsa, Samaris, Živković, Salvio, Krovinović, Pizzi, Cervi, Keaton Parks and Diogo Gonçalves
Forwards: Raúl, Jonas and Seferović